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Abstracts
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Authors Title Reference
Freeman M, Oakley A,
Siller G, Rosen R, Salmon
P, Spelman L, Shumack S,
Rubel D, Birchall N,
Katsamas K
Study to determine the optimal tolerated
regimen of ingenol mebutate (PEP005) gel
for actinic keratosis of the face or face and
scalp click here to view poster

Poster presented at
Summer Academy 08,
American Academy of
Dermatology meeting,
July 30 to August 03, 08,
Chicago, IL, USA
Anderson L, Schmieder
GJ, Werschler WP, Tschen
EH, Ling MR, Stow DB,
Welburn, P

Efficacy and tolerability of ingenol
mebutate (PEP005) gel, 0.025% and
0.05%, for scalp and non-scalp actinic
keratosis click here to view poster
Poster presented at
Summer Academy 08,
American Academy of
Dermatology meeting,
July 30 to August03,  08,
Chicago, IL, USA
Anderson L, Schmieder
GJ, Werschler WP, Tschen
EH, Ling MR, Stow DB,
Katsamas J

Safety and efficacy of ingenol mebutate
(PEP005) gel, 0.025% and 0.05%, for
actinic keratosis click here to view poster


Poster presented at
Summer Academy 08,
American Academy of
Dermatology meeting,
July 30 to August 03, 08,
Chicago, IL, USA
Nowak, R One weed to fight two killers click here to
view article
New Scientist, 7 May
2005, No. 2498, page 16
Siller G, Gebauer K,
Welburn P


Treatment of actinic keratosis with PEP005
Topical Gel click here to view poster


Posted presented at
ACADEMY 06, American
Academy of Dermatology
meeting, 26-30 July 06,
San Diego, CA, USA
Ghoul A, Serova M,
Benhadji KA, Metivier D,
Cvitkovic E, Faivre S,
Ogbourne SM, Welburn P,
Hampson P, Chahal H,
Lord J, Lokiec F, Calvo F,
Raymond E.


PEP005, a novel ingenol angelate
mediates apoptosis in human cancer
cell lines by activation of p38 and MAPK
pathways, via a PKC-dependent
mechanism click here to view abstract




AACR-NCI-EORTC
International
Conference:
Molecular Targets and
Cancer Therapeutics
November 14-18, 2005 -
Poster Session A:
Signal Transduction
Modulators - A189
Ghoul A, Serova M,
Benhadji KA, Metivier D,
Cvitkovic E, Faivre S,
Ogbourne SM, Welburn P,
Hampson P, Chahal H,
Lord J, Lokiec F, Calvo F,
Raymond E.

PEP005, a novel ingenol angelate
mediates apoptosis in human cancer
cell lines by activation of p38 and MAPK
pathways, via a PKC-dependent
mechanism click here to view poster



 AACR-NCI-EORTC
International
Conference:
Molecular Targets and
Cancer Therapeutics
November 14-18, 2005 -
Poster Session A:
Signal Transduction
Modulators - A189
Benhadji KA, Serova M,
Ghoul A, Cvitkovic E,
Ogbourne SM, Welburn P,
Faivre S, Lokiec F, Calvo F,
Raymond E.



Antiproliferative activity of PEP005, a
novelagent activates PKCdelta and
inhibits PKCalpha, alone and in combination
with cytotoxic agents in human solid tumor
cancer cell lines click here to view abstract



AACR-NCI-EORTC
International
Conference:
Molecular Targets and
Cancer Therapeutics
November 14-18, 2005 -
Poster Session A:
Signal Transduction
Modulators - A188
Benhadji KA, Serova M,
Ghoul A, Cvitkovic E,
Ogbourne SM, Welburn P,
Faivre S, Lokiec F, Calvo F,
Raymond E.



Antiproliferative activity of PEP005, a
novelagent activates PKCdelta and
inhibits PKCalpha, alone and in combination
with cytotoxic agents in human solid tumor
cancer cell lines click here to view poster



AACR-NCI-EORTC
International
Conference:
Molecular Targets and
Cancer Therapeutics
November 14-18, 2005 -
Poster Session A:
Signal Transduction
Modulators - A188






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